CD31 Immunohistochemical Staining in Kaposi Sarcoma
نویسندگان
چکیده
منابع مشابه
Immunostaining for CD31 and CD34 in Kaposi sarcoma.
AIMS To evaluate antibodies directed against CD31 (JC70/A) and CD34 (QBEND/10 and anti-HPCA-1) more extensively in Kaposi sarcoma; to assess their value in routine diagnosis; and to compare them with the traditional endothelial cell markers Ulex europaeus agglutinin 1 (UEA-1) and factor VIII related antigen. METHODS Twenty four cases of Kaposi sarcoma were studied retrospectively. All specime...
متن کاملKaposi sarcoma herpesvirus K5 removes CD31/PECAM from endothelial cells.
The transmembrane ubiquitin ligase K5/MIR2 of Kaposi sarcoma herpesvirus (KSHV) mediates internalization and lysosomal degradation of glycoproteins involved in antigen presentation and co-stimulation. In endothelial cells (ECs), K5 additionally reduced expression of CD31/platelet-endothelial cell adhesion molecule (PECAM), an adhesion molecule regulating cell-cell interactions of ECs, platelets...
متن کاملKaposi Sarcoma-Associated Herpesvirus
Kaposi sarcoma-associated herpesvirus (KSHV) is known to be a human carcinogen based on sufficient evidence from studies in humans. This conclusion is based on evidence from epidemiological and molecular studies, which show that KSHV causes Kaposi sarcoma, primary effusion lymphoma, and a plasmablastic variant of multicentric Castleman disease, and on supporting mechanistic data. KSHV causes ca...
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1. Cozen W, Bernstein L, Wang F, Press MF, Mack TM. The risk of angiosarcoma following primary breast cancer. Br J Cancer. 1999;81:532--6. 2. Stewart FW, Treves N. Lymphangiosarcoma in postmastectomy lymphedema: a report of six cases in elephantiasis chirurgica. Cancer. 1948;1:64--81. 3. Tomita K, Yokogawa A, Oda Y, Terahata S. Lymphangiosarcoma in postmastectomy lymphedema (Stewart-Treves synd...
متن کاملKaposi Sarcoma Herpesvirus
First detected by Chang et al. (1994) in Kaposi sarcomas associated with the acquired immune deficiency syndrome (AIDS) (see IARC, 1996) by representational difference analysis, this virus was termed Kaposi-sarcoma-associated herpesvirus, KSHV. KSHV is also associated with primary effusion lymphoma and some cases of multicentric Castleman disease (see Section 2). In keeping with the systematic ...
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ژورنال
عنوان ژورنال: Archives of Pathology & Laboratory Medicine
سال: 2012
ISSN: 1543-2165,0003-9985
DOI: 10.5858/arpa.2012-0153-le